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Prescriptions Dispensed from Canada * are Dispensed by:
Candrug
ID#18985
604.543.8711
Pharmacy Manager:
Amarjit Mann

Pharmacy Address:
202A, 8322-130th Street
Surrey, BC
Canada
V3W 8J9
Toll Free:1-866-995-7387

(*Not all prescriptions dispensed by Candrug.)

Chemical Name: Nicardipine
  Product Manufacturer Dosage  Qty Price(USD)
Cardene 1560 Yamanouchi  20 mg 120 $72.00
Cardene 1561 Yamanouchi  20 mg 240 $112.00
Cardene 1562 Yamanouchi  20 mg 360 $140.00
Cardene SR 571 Yamanouchi  30 mg 112 $84.00
Cardene SR 572 Yamanouchi  30 mg 224 $142.00
Cardene 3822 Yamanouchi  30 mg 112 $81.00
Cardene 3823 Yamanouchi  30 mg 224 $132.00
Cardene 3824 Yamanouchi  30 mg 336 $182.00
Cardene SR 573 Yamanouchi  45 mg 112 $112.00
Cardene SR 574 Yamanouchi  45 mg 224 $212.00
Nicardipine 3819 Generic  20 mg 112 $66.00
Nicardipine 3820 Generic  20 mg 224 $89.00
Nicardipine 3821 Generic  20 mg 336 $114.00
Nicardipine 570 Generic  30 mg 336 $128.00
Nicardipine 3825 Generic  30 mg 112 $68.00
Nicardipine 3826 Generic  30 mg 224 $98.00

Cardene  Information
Cardene is indicated for the prophylaxis of patients with chronic stable angina. For the treatment of hypertension considered to be mild to moderate in severity. Cardene (Nicardipine) capsules for oral administration each contain 20mg or 30mg of nicardipine hydrochloride. Cardene is a calcium ion influx inhibitor and belongs to the dihydropyridine class of calcium channel blockers. Nicardipine should be taken with a little water. Prophylaxis of chronic stable angina: Starting dose: 20 mg every 8 hours titrating upwards as required. Usual effective dose: 30 mg every 8 hours (range of total dose 60 mg - 120 mg per day). Allow at least 3 days before increasing the dose of Cardene to ensure steady state plasma levels have been achieved. Hypertension: Starting dose: 20 mg every 8 hours titrating upwards as required. Usual effective dose: 30 mg every 8 hours (range of total dose 60 mg - 120 mg per day). Use in elderly: Starting dose is 20 mg 3 times a day. Titrate upwards with care as nicardipine may lower systolic pressure more than diastolic pressure in these patients. Children: Cardene is not recommended in patients under the age of 18. Cardene capsules are for oral administration.

Cardene  Side Effects
Majority are not serious and are expected consequences of the vasodilator effects of Cardene. The most frequent side-effects reported are headache, pedal oedema, heat sensation and/or flushing, palpitations, nausea and dizziness. Other side-effects noted in clinical trials include the following: Cardiovascular System: As with the use of other short-acting dihydropyridines in patients with ischaemic heart disease, exacerbation of angina pectoris may occur frequently at the start of treatment with nicardipine capsules. The occurrence of myocardial infarction has been reported although it is not possible to distinguish such an event from the natural course of ischaemic heart disease. Central nervous system: Drowsiness, insomnia, tinnitus, paraesthesia, functional disorders. Skin: Itching, rashes. Hepato-Renal: Impairment, frequency of micturition. Dyspnoea, gastro-intestinal upset and, rarely, depression, impotence and thrombocytopenia, have also been reported. Contraindications: (1) Pregnancy and lactation. (2) Hypersensitivity to nicardipine hydrochloride or other dihydropyridines because of the theoretical risk of cross reactivity. (3) Because part of the effect of nicardipine is secondary to reduced afterload, the drug should not be given to patients with advanced aortic stenosis. Reduction of diastolic pressure in these patients may worsen rather than improve myocardial infarction. (4) Cardene should not be used in cardiogenic shock, clinically significant aortic stenosis, unstable angina, and during or within one month of a myocardial infarction. (5) Cardene should not be used for acute attacks of angina. (6) Cardene should not be used for secondary prevention of myocardial infarction.

The generic alternative is not manufactured by the company that makes the brand product.



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