Brand name: Aloxi
Generic name: Palonosetron Hydrochloride
Used for: Prevent nausea and vomiting in adults
Availability: Brand Aloxi (Purdue Pharma) 0.5mg
How Palonosetron Hydrochloride Works
Palonosetron Hydrochloride is the active ingredient in Aloxi. Aloxi is used to prevent nausea and vomiting in adults after taking certain anti-cancer medicines (chemotherapy). Aloxi is a medicine called an “antiemetic”. Aloxi blocks the action of the natural substance called serotonin which can cause nausea and vomiting. Do not take Aloxi if you are less than 18 years. Aloxi can be taken with or without food.
Palonosetron Hydrochloride Possible Side Effects
Contact your doctor or pharmacist if you experience side effects and they are severe and bothersome. Most of the side effect are manageable and may go away on their own.
Palonosetron Hydrochloride Guidelines
Do not use Aloxi if you are allergic to Palonosetron hydrochloride or any other ingredients in Aloxi capsules. To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Aloxi about any health conditions or problems you may have, including if you have any heart disorder, including an irregular heartbeat, prolongation of the QT interval or a family history of QT prolongation or sudden cardiac death at less than 50 years of age; have low levels of potassium or magnesium; have high blood pressure; have liver or kidney problems; have acute bowel obstruction or a history of repeated constipation; are pregnant or are planning to become pregnant; are breast-feeding or plan to breast-feed; are allergic to other 5-HT3 receptor antagonists such as ondansetron, dolasetron, or granisetron. A rare but potentially life-threatening reaction called Serotonin Syndrome can occur with “antiemetic” medicines such as Aloxi. It can cause serious changes in how your brain, muscles and digestive system work. Serotonin Syndrome symptoms include fever, sweating, shivering, diarrhea, nausea, vomiting; muscle shakes, jerks, twitches or stiffness, overactive reflexes, loss of coordination; fast heartbeat, changes in blood pressure; confusion, agitation, restlessness, hallucinations, mood changes, unconsciousness, and coma. The reaction is more likely to occur if you also take certain other medications or herbal products. Be sure to tell your healthcare professional all the medicines and natural health products (such as St. John’s Wort) you are taking. Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
All prices are in US dollars.
The content on this page has been supplied to BlueSkyDrugs.com by an independent third party contracted to provide information for our website. BlueSkyDrugs relies on these third parties to create and maintain this information and cannot guarantee the medical efficacy, accuracy or reliability of the information that has been provided to us. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a health professional. Please note that not all products, including any referenced in this page, are shipped by our affiliated Canadian Pharmacy. We affiliate with other dispensaries that ship product to our customers from the following jurisdictions: Canada, , New Zealand, Australia, Turkey, Mauritius, India, and United Kingdom. The items in your order maybe shipped from any of the above jurisdictions. The products are sourced from various countries as well as those listed above. Rest assured, we only affiliate with our authorized dispensaries that procure product through reliable sources.