AGRYLIN (Anagrelide) capsules are indicated for the treatment of patients with thrombocythemia, secondary to myeloproliferative disorders, to reduce the elevated platelet count and the risk of thrombosis and to ameliorate associated symptoms. AGRYLIN (Anagrelide) is a prescription medication with the generic name anagrelide hydrochloride. AGRYLIN (Anagrelide) is prescribed for the treatment of patients with thrombocytosis, a condition in which there are too many platelets in the blood. Thrombocytosis is often present in patients with MPDs like Essential Thrombocythemia (ET) and Polycythemia-Vera (P-Vera). The way that AGRYLIN (Anagrelide) works in the body to reduce your platelet count is not fully understood. What is known, however, is that the action of AGRYLIN(Anagrelide) is focused specifically on platelets. As a result, AGRYLIN (Anagrelide) may not have a clinically significant effect on other cells in your blood, such as white cells, which help fight infection, and has no clinically significant effect on red cells, which carry oxygen throughout your body. In addition, AGRYLIN (Anagrelide) does not affect the body's natural processes to clot blood when needed. AGRYLIN (Anagrelide), therefore, lowers your platelet count and offers the safety advantages of platelet-specific action. Patients with ET, P-Vera, and other MPDs who have excessive platelet counts may be candidates to take AGRYLIN (Anagrelide). Your physician uses blood tests to determine the number of platelets in your blood and can best decide if AGRYLIN (Anagrelide) is right for you.
ET and P-Vera and other MPDs are lifelong conditions that usually require long-term treatment. If your physician decides that Agrylin is right for you, take the medication regularly (according to your physician's instruction) to keep your platelet count down.
If you stop treatment with Agrylin, your platelet count will rise rapidly (within a few days) and return to abnormally high levels. Fortunately, Agrylin remains effective and well tolerated in many people who have taken the drug for long periods of time.
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