Brand name: Ibsrela
Generic name: Tenapanor Hydrochloride
Used to: Treat Irritable Bowel Syndrome with constipation
Availability: Brand Ibsrela (Knight Therapeutics Inc), 50 mg
How Ibsrela Works
Ibsrela (Tenapanor) is a medication used in adults to treat irritable bowel syndrome with constipation (IBS-C). This medication is not for use in children, especially children under the age of 6. Ibsrela is an inhibitor of sodium receptors on the surface of the small intestine and colon, which are primarily responsible for the absorption of dietary sodium. By blocking the effects of these receptors, Ibsrela reduces absorption of sodium, which in turn results in an increase in water secretion into the intestines. This accelerates intestinal transit time, and results in a softer stool consistency. Ibsrela has also been shown to reduce abdominal pain by decreasing internal organ hypersensitivity and by decreasing intestinal permeability (looseness of the intestinal walls). All of these effects together allow Ibsrela to help with constipation and abdominal pain caused by IBS-C, leading to a better quality of life.
Ibsrela Possible side effects
Contact your doctor or pharmacist if you experience side effects and they are severe and bothersome. Most of the side effect are manageable and may go away on their own. Some of the common side effects include:
• Gas (flatulence);
• Swelling, or a feeling of fullness or pressure in your abdomen (distension)
Contact your doctor immediately if you notice any of the following side effects:
• Rectal bleeding;
• Severe diarrhea
Ibsrela is not for use in children below 6 years of age, as Ibsrela can cause severe diarrhea and the child could get severely dehydrated. The safety of this medication in patients less than 18 years of age has not been established. Tell your doctor if you are pregnant or breastfeeding, as it is unknown whether or not this medication will harm an unborn baby or a breastfeeding child. You should not use Ibsrela if you are allergic to Tenapanor or if you have a gastrointestinal obstruction. Tell your doctor about any medications you are currently taking or have recently taken in order to reduce the risk of any interactions.
All prices are in US dollars.
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