Brand name: Lynkuet
Generic name: Elinzanetant
Used for: Treatment of moderate to severe hot flashes (vasomotor symptoms) due to menopause
Availability: Brand Lynkuet (Bayer) Not available
How Elinzanetant Works
Elinzanetant is the active ingredient in Lynkuet; it is a drug used to reduce the frequency and severity of hot flashes. It works as a dual neurokinin 1 (NK1) and neurokinin 3 (NK3) receptor antagonist. Modulating the activity of specific hyperactive brain neurons (KNDy neurons) helps regulate the body's temperature control center without using hormones. Elinzanetant has proven effective when taken consistently once daily at bedtime.
Elinzanetant: Possible side effects
Contact your doctor or pharmacist if you experience severe, bothersome side effects. Most side effects are manageable and may go away on their own.
• Dizziness or drowsiness
• Fatigue
• Headache
• Muscle pain
• Nausea
Elinzanetant Guidelines
Do not take Lynkuet if you are allergic to elinzanetant or if you are pregnant, as it may harm an unborn baby. Talk to your doctor about the risks and benefits before you begin treatment. Individuals with severe liver problems should be closely monitored or may be advised against taking this medication. Your doctor may perform blood tests to check your liver function before starting treatment and periodically thereafter. Because this medication may cause dizziness or drowsiness, do not drive or operate heavy machinery until you know how Lynkuet affects you.
The following may interact with elinzanetant, so make sure to tell your doctor about any prescription and over-the-counter medications you are taking:
• CYP3A4 Inhibitors: (e.g., ketoconazole, clarithromycin), which can increase elinzanetant levels.
• Grapefruit Juice: Avoid eating grapefruit or drinking grapefruit juice during treatment.
• Other Medications: Always inform your provider of all vitamins and herbal supplements you are taking.
The generic alternative is not manufactured by the company that makes the brand product.
All prices are in US dollars.
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