BlueSkyDrugs.com will soon offer genuine Myfembree from Canada shipped using Canadian packaging. This medication is manufactured by Pfizer, the worldwide manufacturer of Myfembree. This offer is neither endorsed nor authorized by Pfizer (the United States and Canadian distributor of Myfembree). BlueSkyDrugs.com has no affiliation whatsoever with Pfizer. Inc.
Brand name: Myfembree
Generic name: Relugolix/Estradiol/Norethindrone Acetate
Used for: Manage heavy menstrual bleeding associated with uterine fibroids, moderate to severe pain associated with endometriosis
Availability: Brand Myfembree (Pfizer), 40 mg/1 mg/0.5 mg
How Myfembree Works?
Myfembree (Relugolix/Estradiol/Norethindrone Acetate) is used for the management of heavy menstrual bleeding associated with uterine fibroids and moderate to severe pain associated with endometriosis. Myfembree is a combination medication that contains three active ingredients: relugolix, estradiol, and norethindrone acetate. Relugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist. It works by blocking GnRH receptors in the pituitary gland. This action reduces the production of hormones (estrogen and progesterone) from the ovaries, which helps to shrink uterine fibroids and endometrial tissue, thereby reducing symptoms. Estradiol is an estrogen, and it is a low dose of estrogen to prevent bone loss and other menopausal side effects. Norethindrone acetate is a progestin, and it helps protect against side effects.
Myfembree Possible Side Effects
The most common side effects of Myfembree include:
• Changes in menstrual bleeding
• Decreased libido (low sex drive)
• Fatigue or dizziness
• Hair loss or thinning
• Headaches
• Hot flashes, night sweats, and increased sweating
• Joint or back pain
• Mood changes
• Nausea
Contact your doctor immediately if you experience any of the serious side effects, such as:
• Allergic reaction
• Blood clots and cardiovascular events
• High blood pressure
• High blood sugar
• Liver or gallbladder problems
• Loss of bone density
• Severe mood changes
• Uterine fibroid prolapses or expulsion
Myfembree Guidelines
You should not take Myfembree if you are allergic to relugolix, estradiol, norethindrone, or any of the ingredients in this medication. Before you start taking Myfembree, tell your doctor about your medical history. Myfembree has a boxed warning for the risk of serious blood clots, stroke, and heart attack, especially in women over 35 who smoke or have certain cardiovascular risk factors. It is strictly contraindicated in individuals with a history of these events, uncontrolled high blood pressure, or migraines with aura if over 35. The medication can also cause bone loss, and its use is limited to a maximum of 24 months due to this potentially irreversible effect; therefore, it is contraindicated in women with known osteoporosis. Myfembree is not a contraceptive and can cause early pregnancy loss, so non-hormonal birth control must be used. Patients should be monitored for mood changes, including depression, and for signs of liver problems, as these are additional serious risks. Myfembree is also contraindicated in women with a history of hormone-sensitive cancers, known hepatic impairment, or undiagnosed abnormal uterine bleeding. Tell your doctor about all your medications, including prescription, over-the-counter, vitamins, and herbal supplements. Consult your doctor if you are pregnant or breastfeeding.
All prices are in US dollars.
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