Nubeqa (Darolutamide)

Brand name: Nubeqa
Generic name: Darolutamide
Used for: Treat prostate cancer in adults
Availability: Brand Nubeqa (Bayer) 300 mg

How Darolutamide Works

Nubeqa is used in adults to treat prostate cancer that has not spread to other parts of the body, and to treat prostate cancer that no longer responds to a medicine or surgery that lowers testosterone. This medication belongs to a class of drugs known as anti-androgens (anti-testosterone). Nubeqa contains darolutamide. Darolutamide works by blocking the activity of androgens (like testosterone). This slows the spread of your prostate cancer and the start of disease symptoms. Nubeqa is not for use in patients under the age of 18 years. Always take exactly as your healthcare professional tells you. Check with your doctor or pharmacist if you are not sure. Take your prescribed dose twice a day with food (a snack or meal) at about the same time each day. Do not stop taking Nubeqa without talking to your doctor first. Swallow the tablets whole.

Darolutamide Possible Side Effects

Contact your doctor or pharmacist if you experience side effects and they are severe and bothersome. Most of the side effect are manageable and may go away on their own.
• Bone fracture;
• Cardiac problems (including heart attack, heart disease and heart failure);
• Fatigue (tiredness);
• Rash;
• Pain in arms and legs

Darolutamide Guidelines

Do not use Nubeqa if you are allergic to darolutamide or any of the other ingredients of this medicine. To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Nubeqa about any health conditions or problems you may have, including if you suffer from a lactose intolerance; have or have had liver or kidney problems; have a partner who is pregnant or may become pregnant. Nubeqa may harm your unborn baby or may make your partner lose the baby. Men who are sexually active with a pregnant woman must use a condom during and for 3 months after the last dose. If your sexual partner may become pregnant, highly effective birth control must be used during and for 3 months after treatment. Talk with your healthcare professional if you have questions about birth control. If your sexual partner becomes pregnant while you are taking Nubeqa, tell your healthcare professional right away. Nubeqa may affect your ability to have a child. Talk to your doctor if this is a concern for you. Do not donate sperm while taking Nubeqa and for 3 months after stopping Nubeqa. Nubeqa is not for use in women. Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines. The drugs that may interact with Nubeqa include rifampicin – used to treat bacterial infections; carbamazepine, phenobarbital – used to treat epilepsy; St. John's Wort (hypericum perforatum) – a herbal product used mainly to treat depression; rosuvastatin, fluvastatin, and atorvastatin – used to treat high cholesterol; methotrexate – used to treat severe joint inflammation, severe cases of the skin disease psoriasis, and cancers; sulfasalazine – used to treat inflammatory bowel disease; itraconazole – used to treat fungal infections. Nubeqa may cause abnormal blood test results. This includes abnormal blood cell counts and liver enzymes. Your healthcare professional will decide when to perform blood tests and will interpret the results.