Tribenzor (Olmesartan Medoxomil/Amlodipine/Hydrochlorothiazide)

Brand name: Tribenzor, Sevikar HCT
Generic name: Olmesartan medoxomil, amlodipine, hydrochlorothiazide
Used for: Treat blood pressure (hypertension)
Availability: Brand Tribenzor (MSD, Daiichi Sankyo), 20mg/5mg/12.5mg, 40mg/10mg/25mg, 40mg/5mg/12.5mg,40mg/10mg/12.5mg, 40mg/5mg/25mg

How Olmesartan medoxomil, amlodipine, hydrochlorothiazide Works

Tribenzor is a prescription medicine used to lower blood pressure (hypertension). Medicines that lower blood pressure lower your chance of having a stroke or heart attack. Tribenzor is not for use as the first medicine to treat your high blood pressure. Tribenzor contains 3 different prescription medications: amlodipine, a calcium channel blocker; olmesartan medoxomil, an angiotensin receptor blocker; and hydrochlorothiazide, a diuretic (water pill). Olmesartan is an angiotensin receptor blocker (ARB) and amlodipine is a calcium channel blocker. They both work by relaxing blood vessels so blood can flow more easily. Hydrochlorothiazide is called a "water pill" (diuretic) and causes your body to get rid of extra salt and water by making more urine. It is not known if Tribenzor is safe and works in children.

Olmesartan medoxomil, amlodipine, hydrochlorothiazide Possible Side Effects

Contact your doctor or pharmacist if you experience side effects and they are severe and bothersome. Most of the side effect are manageable and may go away on their own.
• Allergic reactions. Hydrochlorothiazide, one of the medicines in Tribenzor can cause allergic reactions;
• Changes in body salts (such as sodium and potassium), and body fluids;
• Dizziness, nausea;
• Diarrhea;
• Eye problems that may lead to vision loss. Tell your doctor right away if you have decrease in vision, eye pain;
• Headache;
• Harm to an unborn baby causing injury or death;
• Kidney problems. Kidney problems may get worse in people that already have kidney disease;
• Low Blood Pressure (hypotension);
• Muscle twitching (spasms);
• Swelling (edema) of the ankles, feet, and hands;
• Stuffy or runny nose and sore throat;
• Tiredness;
• Urinary tract infection;
• Upper respiratory tract infection;
• Worsening chest pain or heart attack.

Olmesartan medoxomil, amlodipine, hydrochlorothiazide Guidelines

Do not take Tribenzor if you have low or no urine output; are allergic to other Sulfonamide type medicines; are taking aliskiren and have diabetes. Before taking Tribenzor, tell your doctor if you are allergic to any of the ingredients in Tribenzor; have liver problems; have heart problems; liver disease; dehydration; untreated electrolytes imbalance (such as high/low potassium, low magnesium, high calcium); have kidney problems; have lupus; are vomiting or have a lot of diarrhea; have any other medical conditions; are pregnant or plan to become pregnant; are breast feeding or plan to breast feed. One of the medicines in Tribenzor can pass into your breast milk and may harm your baby. Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Some of your other medicines and Tribenzor could affect each other, causing serious side effects. Especially tell your doctor if you are taking water pills (diuretics); other medicines for high blood pressure or a heart problem; potassium supplements or using salt substitute containing potassium; diabetes medicine including insulin; narcotic pain medicine; sleeping pills and anti-seizure medicines called barbiturates; lithium, a medicine used to treat certain kinds of depression; medicines used to treat pain or arthritis such as aspirin or non-steroidal anti-inflammatory drugs (NSAIDs); steroids; cholesterol lowering medicines. Avoid drinking alcohol during treatment with Tribenzor as it can cause you to have low blood pressure.

If you have diabetes, this product may affect your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. This product may affect your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist. This medication may make you more sensitive to the sun. It may also increase your risk for skin cancer, especially if you take it for a long time. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned, have skin blisters/redness, or notice new or changed moles/skin lesions. Older adults may be more sensitive to the side effects of this drug, especially dizziness and change in the amount of urine (kidney problems).